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Status |
Public on Apr 10, 2007 |
Title |
Olanzapine vs. Saline rat pfc |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
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Summary |
Male Sprague-Dawley albino rats (Charles River) initially weighting approximately 200 grams were randomly assigned to one of the following: 1) olanzapine (2 mg/kg/day, I.P.) (N=20) or 2) Saline (N=20) and administered olanzapine or saline for 21 days. Frontal cortex (N=4/group) was dissected and homogenized for microarray, QPCR and western blotting following previous methods (Fatemi et al. 2003; Brooks et al. 2003). RNA isolation, cDNA preparation, microarray hybridization and QPCR followed previous methods (Brooks et al. 2003).
Keywords = olanzapine Keywords = frontal cortex Keywords: repeat sample
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Contributor(s) |
Fatemi SH, Reutiman TJ, Bell C, Nos L, Fried P, Folsom TD, Snow AV, Brooks AI, Pearce DA |
Citation(s) |
16407901 |
Submission date |
Apr 20, 2005 |
Last update date |
Jul 31, 2017 |
Contact name |
S. Hossein Fatemi |
E-mail(s) |
fatem002@umn.edu
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Phone |
612-626-3633
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Fax |
612-624-8935
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Organization name |
University of Minnesota
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Department |
Department of Psychiatry, Division of Neuroscience Research
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Street address |
420 Delaware St SE, MMC 392
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City |
Minneapolis |
State/province |
MN |
ZIP/Postal code |
55455 |
Country |
USA |
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Platforms (1) |
GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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Samples (8)
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Relations |
BioProject |
PRJNA92149 |
Supplementary data files not provided |
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