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Series GSE25770 Query DataSets for GSE25770
Status Public on Sep 01, 2011
Title Gene expression in astrocytes upon sustained GSK-3 inhibition by small molecule
Organism Mus musculus
Experiment type Expression profiling by array
Summary In order to identify molecular targets that mediates the stimulation of astrocyte's migration upon sustained specific inhibition of GSK-3, we have employed whole genome microarray expression profiling. Murine cortical-striatal astrocytes grown in primary culture were treated in vitro for 48 h with either 1 micromolar Ro3303544, or control medium (final equivalent concentration of DMSO), or washed-out for 48h in control medium after an initial 48h treatment with 1 micromolar Ro3303544.
 
Overall design The three different conditions: Ctrl, Ro and wash-out (each in duplicate) were compared.
 
Contributor(s) Renault-Mihara F, Okano H
Citation(s) 21898827
Submission date Dec 02, 2010
Last update date Jan 12, 2017
Contact name francois frederic renault-mihara
E-mail(s) frenaultpro@yahoo.fr
Organization name Keio University School of Medicine
Department Physiology
Lab Physiology 1
Street address 35 Shinanomachi, Shinjuku-ku
City Tokyo
ZIP/Postal code 160-8582
Country Japan
 
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (6)
GSM634052 control medium (10% FBS): replicate 1
GSM634053 control medium (10% FBS): replicate 2
GSM634054 treated 48h with 1 micromolar Ro3303544: replicate 1
Relations
BioProject PRJNA134075

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE25770_RAW.tar 13.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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