|
| Status |
Public on Jun 01, 2011 |
| Title |
Respiratory chain protein analysis and gene expression profiles of fibroblast cell lines from 9 patients with SURF1 gene mutations |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Upregulation of CI, CIII and CV at a protein but not mRNA level in LSCOX cell with COX deficiency due to SURF1 mutations compared to control – evidence for posttranscriptional compensatory mechanism.
|
| |
|
| Overall design |
Two-condition experiment, patients vs. controls cells. Biological replicates: 3 controls and 9 patients, independently grown and harvested.
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| |
|
| Contributor(s) |
Kovarova N, Cizkova Vrbacka A, Stranecky V, Pecina P, Pronicka E, Kmoch S, Houstek J |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Dec 28, 2010 |
| Last update date |
Feb 22, 2018 |
| Contact name |
Viktor Stranecky |
| Organization name |
Charles University
|
| Department |
1st Faculty of Medicine
|
| Lab |
Institute of inherited metabolic disorders
|
| Street address |
Ke Karlovu 2
|
| City |
Prague |
| ZIP/Postal code |
128 00 |
| Country |
Czech Republic |
| |
|
| Platforms (1) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA136773 |
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