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| Status |
Public on Jan 01, 2013 |
| Title |
Coordinated Chromatin Remodeling induced by Demethylation requires SRCAP mediated H2A.Z exchange [Methylation] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
|
| Summary |
Genome wide DNA methylation profiling of RKO cells with combination treatments of non-target siRNA or SRCAP siRNA and PBS or 1uM 5-Aza-CdR treatment. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across 27,578 CpGs in treated RKO cells. Samples included cells under 4 different treatments. The sample treated with non target siRNA and PBS serves as control sample.
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| Overall design |
Bisulphite converted DNA from the 4 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2
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| |
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| Contributor(s) |
Yang X, Noushmehr H, Jones PA |
| Citation(s) |
22479200 |
| Submission date |
Jan 04, 2011 |
| Last update date |
Jan 02, 2015 |
| Contact name |
Houtan Noushmehr |
| Phone |
310-570-2362
|
| Organization name |
Henry Ford Health System
|
| Street address |
2799 W. Grand Blvd
|
| City |
Detroit |
| State/province |
MI |
| ZIP/Postal code |
48202 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL8490 |
Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2) |
|
| Samples (4)
|
| GSM648519 |
Genome DNA from RKO cells treated with Non-target siRNA and PBS for 72hr |
| GSM648520 |
Genome DNA from RKO cells treated with Non-target siRNA and 5-Aza-CdR for 72hr |
| GSM648521 |
Genome DNA from RKO cells treated with SRCAP siRNA and PBS for 72hr |
| GSM648522 |
Genome DNA from RKO cells treated with SRCAP siRNA and 5-Aza-CdR for 72hr |
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| This SubSeries is part of SuperSeries: |
| GSE26685 |
Coordinated Chromatin Remodeling induced by Demethylation requires SRCAP mediated H2A.Z exchange |
|
| Relations |
| BioProject |
PRJNA142265 |
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