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Series GSE26717 Query DataSets for GSE26717
Status Public on Jan 20, 2011
Title Microarray analysis of R7 and R8 targeting
Organism Drosophila melanogaster
Experiment type Expression profiling by array
Summary The formation of neuronal connections requires the precise guidance of developing axons towards their targets. In the Drosophila visual system, photoreceptor neurons (R cells) project from the eye into the brain. These cells are grouped into some 750 clusters comprised of eight photoreceptors or R-cells each. R cells fall into three classes, R1-R6, R7 and R8. Posterior R8 cells are the first to project axons into the brain. How these axons select a specific pathway is not known.
Here, we used a microarray-based approach to identify genes expressed in R7 and R8 neurons as they extend into the brain.
 
Overall design We used microarray analysis to measure gene expression changes when the transcription factor Runt is misexpressed in eye discs and conversely when eye discs are rendered mutant for the Senseless transcription factor.
 
Contributor(s) Pappu KS, Morey M, Nern A, Spitzweck B, Dickson BJ, Zipursky SL
Citation(s) 21490297
Submission date Jan 19, 2011
Last update date Aug 28, 2018
Contact name S Lawrence Zipursky
Organization name Howard Hughes Medical Institute
Department Biological Chemistry
Lab 5-784 MacDonald Research Laboratories
Street address 675 Charles E. Young Drive South
City Los Angeles
State/province California
ZIP/Postal code 90095
Country USA
 
Platforms (1)
GPL1322 [Drosophila_2] Affymetrix Drosophila Genome 2.0 Array
Samples (12)
GSM657883 Drosophila-ro-Gal4xUAS-runt-1
GSM657884 Drosophila-ro-Gal4xUAS-runt-2
GSM657885 Drosophila-ro-Gal4xUAS-runt-3
Relations
BioProject PRJNA136363

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE26717_RAW.tar 23.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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