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| Status |
Public on Apr 01, 2011 |
| Title |
Expression data from HeLa cells transiently transfected with control siRNA or SON siRNA |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
SON is a large Ser/Arg (SR)-related protein localized in nuclear speckles. SON siRNA causes defects in mitotic progression and genome instability. We used microarrays to detail the pattern of gene expression after SON knockdown.
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| Overall design |
HeLa cells were grown in 100 mm dishes and transfected with negative control siRNA or SON siRNA (400 pmol). Then, cells were harvested after 66 hours and RNAs were isolated. Microarrays were performed using GeneChip Human Genome U133A 2.0 (Affymetrix).
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| |
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| Contributor(s) |
Ahn E, DeKelver RC, Lo M, Nguyen TA, Matsuura S, Boyapati A, Pandit S, Fu X, Zhang D |
| Citation(s) |
21504830 |
| Submission date |
Jan 26, 2011 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Dong-Er Zhang |
| E-mail(s) |
d7zhang@ucsd.edu
|
| Phone |
858-822-5372
|
| Organization name |
University of California San Diego
|
| Department |
Cancer Center
|
| Lab |
Zhang
|
| Street address |
3855 Health Sciences Drive, Mail Stop 0815
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92093 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA135949 |
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