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| Status |
Public on Apr 01, 2011 |
| Title |
Peripheral blood cells expression data form 7 patients with severe pdm(H1N1) influensa and 7 gender and age matched healthy controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Using PAXgene tubes, peripheral blood samples were collected from seven patients >18 years with documented pdm(H1N1) influenza, bilateral chest infiltrates, and in need of ventilation support. Significant co-morbidity was exclusion criterion. Expression profiles were compared with 7 age matched controls. Using a false discovery rate < 5% and an absolute fold change > 2, 370 genes were differentially expressed in case and controls.
A second sample was collected after ca 6 days in the 7 patients and temporal changes in expression profiles investigated. Over expressed putative mediators of inflammatory lung dammage were measured on the protein level.
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| Overall design |
14 patient samples (7 paired samples) and 7 control samples were performed.
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| Contributor(s) |
Berdal J, Olstad OK, Jonassen CM |
| Citation(s) |
21781987 |
| Submission date |
Feb 08, 2011 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Jan-Erik Berdal |
| E-mail(s) |
jan-erik.berdal@hotmail.com
|
| Phone |
004748205817
|
| Organization name |
AHUS
|
| Department |
medical department
|
| Street address |
Sykehusvn.
|
| City |
Lørenskog |
| State/province |
Akershus |
| ZIP/Postal code |
1474 |
| Country |
Norway |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (21)
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| Relations |
| BioProject |
PRJNA137417 |
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