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Series GSE2774 Query DataSets for GSE2774
Status Public on Dec 06, 2005
Title Identification of tumor immune evasion mechanism using P0 and P3 cell lines
Organism Mus musculus
Experiment type Expression profiling by array
Summary The emergence of immune resistance variants during immunotherapy is poorly understood. We generated a highly immune resistant cell line (P3) from a susceptible cell line (P0) by subjecting it to 3 rounds of in vivo immune selection. Subsequently, microarray analysis of P0 and P3 was performed to identify genes that may contribute to the increase in immune resistance.
Keywords: cell type comparison
Overall design Four experimental replicates were prepared for each cell line. P0 is the control cell line, and P3 is the experimental/resistant cell line.
Contributor(s) Lin K, Hung C, Peng S, Jie C, Pardoll DM, Wu T
Citation(s) 17308126
Submission date Jun 06, 2005
Last update date Feb 11, 2019
Contact name Ken-Yu Lin
Phone 410-614-4906
Organization name Johns Hopkins University School of Medicine
Department Pathology
Lab T.-C. Wu
Street address 720 Rutland Ave, Ross 512
City Baltimore
State/province MD
ZIP/Postal code 21205
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (8)
GSM60397 tumor immune evasion - P0 cell line
GSM60398 tumor immune evasion - P0 cell line-replicate 2
GSM60400 tumor immune evasion - P0 cell line-replicate 3
BioProject PRJNA92309

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