 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Mar 22, 2011 |
| Title |
Gene expression profiling of mouse sclera during post-natal development |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Although there have been studies conducted on cornea and retina growth and development, postnatal gene expression studies on sclera growth during postnatal growth has not been well characterised. Given that the mouse genome has 85% homology to the human genome and has been completely sequenced, mouse model for the study of ocular growth has advantages over other animal models. Thus, we aimed to study the biology and genetics behind sclera growth during post-natal development in Balb/cJ mice as a means to understand genetic changes that cause scleral growth and development during post-natal eye development
The purpose of this study was to identify the genes underlying the development of mouse sclera post-natal growth of the posterior chamber of the eye using microarray
|
| |
|
| Overall design |
Total RNA was isolated from single cryogenically ground mouse sclera (n=30, 6 samples each from week 1-, 2-, 3-, 6-and 8-old mice), reverse-transcribed and hybridized onto a Affymetrix mouse gene 1.0 ST array.We sought to use microarray to determine the gene expression profiles of mouse sclera from different age groups and identify the developmental genes that are involved in postnatal ocular growth.
|
| |
|
| Contributor(s) |
Lim W, Kwan JL, Goh LK, Beuerman RW, Barathi VA |
| Citation(s) |
22736935 |
| Submission date |
Mar 21, 2011 |
| Last update date |
Aug 16, 2019 |
| Contact name |
Wan'e Lim |
| E-mail(s) |
lim.wan.e@seri.com.sg
|
| Phone |
+65 63224568
|
| Fax |
+65 63224599
|
| Organization name |
Singapore Eye Research Institute
|
| Street address |
11 Third Hospital Ave
|
| City |
Singapore |
| ZIP/Postal code |
168751 |
| Country |
Singapore |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (30)
|
| GSM693990 |
Sclera week 1, biological rep4 |
| GSM693991 |
Sclera week 1, biological rep5 |
| GSM693992 |
Sclera week 1, biological rep6 |
| GSM693993 |
Sclera week 2, biological rep1 |
| GSM693994 |
Sclera week 2, biological rep2 |
| GSM693995 |
Sclera week 2, biological rep3 |
| GSM693996 |
Sclera week 2, biological rep4 |
| GSM693997 |
Sclera week 2, biological rep5 |
| GSM693998 |
Sclera week 2, biological rep6 |
| GSM693999 |
Sclera week 3, biological rep1 |
| GSM694000 |
Sclera week 3, biological rep2 |
| GSM694001 |
Sclera week 3, biological rep3 |
| GSM694002 |
Sclera week 3, biological rep4 |
| GSM694003 |
Sclera week 3, biological rep5 |
| GSM694004 |
Sclera week 3, biological rep6 |
| GSM694005 |
Sclera week 6, biological rep1 |
| GSM694006 |
Sclera week 6, biological rep2 |
| GSM694007 |
Sclera week 6, biological rep3 |
| GSM694008 |
Sclera week 6, biological rep4 |
| GSM694009 |
Sclera week 6, biological rep5 |
| GSM694010 |
Sclera week 6, biological rep6 |
| GSM694011 |
Sclera week 8, biological rep1 |
| GSM694012 |
Sclera week 8, biological rep2 |
| GSM694013 |
Sclera week 8, biological rep3 |
| GSM694014 |
Sclera week 8, biological rep4 |
| GSM694015 |
Sclera week 8, biological rep5 |
| GSM694016 |
Sclera week 8, biological rep6 |
|
| Relations |
| BioProject |
PRJNA139775 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE28056_RAW.tar |
117.9 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
|
|
|
|
 |
Less...
More...