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Status |
Public on Dec 30, 2011 |
Title |
IL-22 down-regulates filaggrin expression and affects expression of profilaggrin processing enzymes by keratinocytes |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Genome-wide analysis of gene expression after stimulation with cytokines to assess the main processes, molecular functions and cellular components affected as well as genes related to skin barrier function.
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Overall design |
HaCaT cells were exposed to IL-22 (200ng/ml) for 12h. The cells were lysed, total RNA was extracted and microarray study was performed on Illumina HT12 platform.
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Contributor(s) |
Ogg GS, Gutowska-Owsiak D |
Citation(s) |
21564072 |
Submission date |
Mar 24, 2011 |
Last update date |
Aug 13, 2018 |
Contact name |
Stephen Taylor |
E-mail(s) |
stephen.taylor@imm.ox.ac.uk
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Phone |
+44 1865 222640
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Organization name |
CBRG
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Street address |
Headington
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City |
Oxford |
ZIP/Postal code |
OX3 9DS |
Country |
United Kingdom |
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Platforms (1) |
GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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Samples (6)
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Relations |
BioProject |
PRJNA139677 |