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Series GSE28160 Query DataSets for GSE28160
Status Public on Sep 25, 2011
Title Significant Effects of Antiretroviral Therapy on Global Gene Expression in Brain Tissues of Patients with HIV-Associated Neurocognitive Disorders
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Antiretroviral therapy (ART) has reduced morbidity and mortality in HIV infection; however HIV-1-associated neurocognitive disorders (HAND) persist despite treatment. We used microarray analysis in post-mortem brain tissues to determine ART effectiveness in the brain and to identify molecular signatures of HAND under ART.
 
Overall design We performed microarray analysis using Affymetrix Arrays in portmortem brain tissues from seven treated and eight untreated HAND patients and six uninfected controls.
 
Contributor(s) Borjabad A, Volsky DJ
Citation(s) 21909266
Submission date Mar 24, 2011
Last update date Mar 25, 2019
Contact name Alejandra Borjabad
E-mail(s) ab2612@columbia.edu
Phone 9175574628
Organization name St.Luke's-Roosevelt Hospital Center
Department Medicine
Lab Molecular Virology
Street address 432 West 58th, Street
City New York
State/province NY
ZIP/Postal code 10019
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (35)
GSM697483 Control brain 1, biological rep1
GSM697484 Control brain 2, biological rep1
GSM697485 Control brain 3, biological rep1
Relations
BioProject PRJNA139681

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28160_RAW.tar 157.7 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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