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Series GSE28197 Query DataSets for GSE28197
Status Public on Dec 29, 2011
Title Expression analysis of stepwise induction of iPS cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary We were able to achieve an initial stable intermediate phase by the transduction of Oct4, Klf4, and c-Myc. Furthermore, over-expression of Sox2 in these intermediate stage cells leads to final iPS cell phase.
After examining the gene expression profiles from the initial to final iPS cell phases, we have identified Sox2 downstream genes important for iPS cell induction.
Overall design 4 groups of cells are analyzed. Each group contains cells from 4 indepent dishes. The four groups are: ES cells, iPS cells, intermediate stage cells (OKM cells) and MEFs
Contributor(s) Jianxin B, Zhaoyu L
Citation(s) 21956995
Submission date Mar 27, 2011
Last update date Jun 14, 2018
Contact name Jianxin Bao
Organization name Washington University
Street address Box 8114
City Saint Louis
ZIP/Postal code 63110
Country USA
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (16)
GSM698095 4384 - 3F-SOX2-CD1- 3
GSM698096 4375 - MEF- 2
GSM698097 4381 - 3F-CD1- 4
BioProject PRJNA139631

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28197_RAW.tar 3.1 Mb (http)(custom) TAR
GSE28197_non-normalized.txt.gz 1.6 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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