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Series GSE28300 Query DataSets for GSE28300
Status Public on Apr 01, 2011
Title Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene expression approach to differences in stress response between human skin fibroblasts derived from chronologically young (~20 years) and old (~90 years) subjects. Expression of CDKN2A was most different between fibroblasts from young and old subjects and
 
Overall design Human skin fibroblasts were isolated from skin biopsies of 6 young subjects and 6 old subjects and were treated for 3 hours and 3 days with 0.6 uM rotenone. Also there were control samples, not treated but grown for 3 days, making a total of 36 samples. No experimental replicates were included. The expression of CDKN2A was quantified in the same RNA samples by real-time PCR.
 
Contributor(s) Dekker P, Gunn D, McBryan T, Adams P, Maier AB
Citation(s) 22721680
Submission date Mar 31, 2011
Last update date Jul 09, 2018
Contact name Andrea B Maier
E-mail(s) a.b.maier@lumc.nl
Organization name LUMC
Street address postbox 9600
City 2300 RC
ZIP/Postal code Leiden
Country Netherlands
 
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (36)
GSM700222 Skin_fibroblasts_non-treated_3_days_subject_S030
GSM700223 Skin_fibroblasts_0.6_uM_rotenone_3_days_subject_S030
GSM700224 Skin_fibroblasts_0.6_uM_rotenone_3_hours_subject_S030
Relations
BioProject PRJNA139487

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28300_RAW.tar 86.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
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