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Series GSE28405 Query DataSets for GSE28405
Status Public on Dec 31, 2011
Title Genome-wide gene expression analysis of human whole-blood samples in in response to dengue disease
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We looked at the whole-blood transcriptional profiling on dengue patients sampled within 72h of fever presentation and compared the signatures with autologous samples drawn at defervescence and convalescence and to control patients with fever of other etiology.
Our data show that the early response in patients mimics those previously only described in vitro and suggests that this innate immune responses may initiate the later adaptive immune responses.
 
Overall design Total RNA obtained from whole-blood of dengue patients with fever presentation, defervescence and convalescence are compared. Also, dengue patients with fever presentation are compared with control patients which are with fever of other etiology. 119 samples are analysed, which include 31 dengue patients and 26 control patients.
 
Contributor(s) Ling L, Tolfvenstam T, Lindblom A, Hibberd ML
Citation(s) 21810247
Submission date Apr 05, 2011
Last update date Apr 04, 2012
Contact name Ahmad Nazri Mohamed Naim
E-mail(s) mohamedan@gis.a-star.edu.sg
Phone 65-98547654
Organization name Genome institute of Singapore
Department Infectious disease
Lab lab 1
Street address 60 Biopolis Street, Genome, #02-01
City Singapore
ZIP/Postal code 138672
Country Singapore
 
Platforms (1)
GPL2700 Sentrix HumanRef-8 Expression BeadChip
Samples (119)
GSM702006 Control_sample 1
GSM702007 Control_sample 2
GSM702008 Control_sample 3
Relations
BioProject PRJNA139183

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28405_non-normalized.txt.gz 11.6 Mb (ftp)(http) TXT
Processed data included within Sample table

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