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| Status |
Public on Oct 17, 2013 |
| Title |
Induction of trophoblast stem cells from embryonic stem cells by forced repression of Oct3/4. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To characterize the transdifferentiation of embryonic stem (ES) cells into trophoblast stem (TS) cells triggered by forced repression of Oct3/4, we performed whole-genome expression analysis after tetracycline (Tet)-induced knockout of Oct3/4.
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| Overall design |
A Tet-inducible Oct3/4 knockout ES cell line ZHBTc4 was treated with Tet for 4 days in the presence of FGF4 and mouse embryonic fibroblasts (MEFs). A total of 21 samples from Day 0 to Day 4 were analyzed in three biological replicates.
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| |
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| Contributor(s) |
Adachi K, Nikaido I, Ueda HR, Niwa H |
| Citation(s) |
24120664 |
| Submission date |
Apr 07, 2011 |
| Last update date |
Mar 06, 2018 |
| Contact name |
Itoshi NIKAIDO |
| E-mail(s) |
itoshi.nikaido@riken.jp
|
| Organization name |
RIKEN
|
| Department |
Center for Biosystems Dynamics Research
|
| Lab |
Laboratory for Bioinformatics Research
|
| Street address |
2-1 Hirosawa
|
| City |
Wako |
| State/province |
Saitama |
| ZIP/Postal code |
351-0198 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (21)
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| This SubSeries is part of SuperSeries: |
| GSE28455 |
Sox2-regulatory networks in embryonic and trophoblast stem cells |
|
| Relations |
| BioProject |
PRJNA143233 |
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