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Series GSE28476 Query DataSets for GSE28476
Status Public on Apr 09, 2011
Title Characterization of differential gene expression in adrenocortical tumors harbouring β-catenin (CTNNB1) mutations.
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Mutations of β-catenin gene (CTNNB1) are frequent in adrenocortical adenomas (AA) and carcinomas (ACC). However, the target genes of CTNNB1 have not yet been identified in adrenocortical tumors.
Our objective was to identify genes de-regulated in adrenocortical tumors harbouring CTNNB1 genetic alterations.
 
Overall design We compared gene expression profiles of AA with (n: 3) and without (n: 4) CTNNB1 mutations using Affymetrix arrays.
 
Contributor(s) Durand J, Bourdeau I
Citation(s) 21565795
Submission date Apr 08, 2011
Last update date Mar 25, 2019
Contact name julien durand
E-mail(s) juliend667@gmail.com
Phone 514-890-8000
Organization name CRCHUM
Department Biomedicale Science
Street address 3840 Rue Saint-Urbain
City Montreal
State/province QC
ZIP/Postal code H2W 1T8
Country Canada
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (8)
GSM703788 Pool of 62 normal adrenal glands
GSM703789 Adrenocortical adenoma with CTNNB1 mutation (S45P)
GSM703790 Adrenocortical adenoma with CTNNB1 mutation (T41A)
Relations
BioProject PRJNA139317

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28476_RAW.tar 38.5 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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