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| Status |
Public on Oct 18, 2011 |
| Title |
Expression data from treatment of actinomycin D and triptolide on MCF7 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Expression data from treatment of actinomycin D (2.5uM) and triptolide (500 nM) on MCF7 cells for 2, 4 and 6 hours.
We used microarrays to explore the mechanism of triptolide action.
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| Overall design |
MCF7 cells were treated with actinomycin D or triptolide for 2, 4 and 6 hours, RNA was extracted and hybridization on Affymetrix microarrays. Data were normalized by RMA.
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| Contributor(s) |
Wei G, Golub TR |
| Citation(s) |
22516262 |
| Submission date |
Apr 15, 2011 |
| Last update date |
Jan 17, 2017 |
| Contact name |
Guo Wei |
| E-mail(s) |
guowei@broadinstitute.org
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| Organization name |
Broad Institute or MIT and Harvard
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| Street address |
7 Cambridge Center
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| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02142 |
| Country |
USA |
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| Platforms (1) |
| GPL3921 |
[HT_HG-U133A] Affymetrix HT Human Genome U133A Array |
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| Samples (18)
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| GSM710152 |
DMSO 4 hours, replicate 2 |
| GSM710153 |
DMSO 6 hours, replicate 1 |
| GSM710154 |
DMSO 6 hours, replicate 2 |
| GSM710155 |
Actinomycin D, 2 hours, replicate 1 |
| GSM710156 |
Actinomycin D, 2 hours, replicate 2 |
| GSM710157 |
Actinomycin D, 4 hours, replicate 1 |
| GSM710158 |
Actinomycin D, 4 hours, replicate 2 |
| GSM710159 |
Actinomycin D, 6 hours, replicate 1 |
| GSM710160 |
Actinomycin D, 6 hours, replicate 2 |
| GSM710161 |
Triptolide, 2 hours, replicate 1 |
| GSM710162 |
Triptolide, 2 hours, replicate 2 |
| GSM710163 |
Triptolide, 4 hours, replicate 1 |
| GSM710164 |
Triptolide, 4 hours, replicate 2 |
| GSM710165 |
Triptolide, 6 hours, replicate 1 |
| GSM710166 |
Triptolide, 6 hours, replicate 2 |
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| Relations |
| BioProject |
PRJNA138867 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE28662_RAW.tar |
40.8 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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