|
| Status |
Public on Jun 17, 2011 |
| Title |
Exon array analysis in primary human fibroblasts |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Exon usage analysis in in vitro cultured fibroblast cells. To assay the genome-wide splicing changes during cellular senescence, we performed splicing analysis on young and old normal fibroblasts, and in fibroblasts +/- tert (telomerase protein subunit Tert immortalized).
|
| |
|
| Overall design |
We analyzed primary fibroblasts from 5 healthy subjects at various passages and from 2 Hutchinson-Gilford Progeria Syndrome (HGPS) patients using the Affymetrix Human Exon 1.0 ST platform. Two or three technical replicates were performed.
|
| |
|
| Contributor(s) |
Kan C, Collins F |
| Citation(s) |
21670498 |
| Submission date |
Apr 26, 2011 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Kan Cao |
| E-mail(s) |
kcao@umd.edu
|
| Organization name |
University of Maryland
|
| Department |
CBMG
|
| Street address |
2219 Bioscience Research building
|
| City |
College Park |
| ZIP/Postal code |
20742 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
| GPL5188 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
| Samples (34)
|
|
| Relations |
| BioProject |
PRJNA140579 |
Less...
More...