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| Status |
Public on Apr 29, 2011 |
| Title |
Development of decidual cell polyploidy and bi-nucleation necessitates mitochondrial activity |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In the present study, to better define the aspects of decidual cell polyploidy, we isolated pure polyploid and non-polyploid decidual cell populations from the in vivo decidual bed. Three independent RNA pools prepared for each population were then subjected to the Affymetrix gene chip analysis for the whole mouse genome transcripts.
Our data revealed up-regulation of 1015 genes and down-regulation of 1207 genes in the polyploid populations, as compared to the non-polyploid group.
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| Overall design |
We analyzed whole gnenome transcription from non-polyploid and polyploid cell populations using the Affymetrix GeneChip® Mouse Gene 1.0 ST Array . 3 replicates were performed.
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| Contributor(s) |
Ma X, Gao F, Rusie A, Hemingway J, Blackwell A, Sroga JM, Jegga AG, Das SK |
| Citation(s) |
22046353 |
| Submission date |
Apr 28, 2011 |
| Last update date |
Oct 31, 2019 |
| Contact name |
xinghong ma |
| E-mail(s) |
xinghong.ma@cchmc.org
|
| Organization name |
Cincinnati Children's Hospital Medical Center
|
| Street address |
3333 Burnet Avenue
|
| City |
Cincinnati |
| State/province |
OH |
| ZIP/Postal code |
45229 |
| Country |
USA |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA140573 |
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