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| Status |
Public on May 03, 2011 |
| Title |
Identification of Unique Therapeutic Targets in Esophageal Squamous Cell Carcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We utilized tissue microdissection and expression microarrays to measure ex vivo gene expression profiles in twelve cases of patient-matched normal basal epithelial cells, normal differentiated squamous epithelium, and cancer.
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| Overall design |
The data set from the precisely-dissected, dividing basal cell layer was used as a ‘biological filter’ to identify genes that were specifically dysregulated in tumors, and not simply increased as a consequence of normal growth.
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| Contributor(s) |
Yan W, Shih J, Rodriguez-Canales J, Hipp J, Player A, Hu N, Goldstein AM, Taylor PR, Emmert-Buck MR, Erickson HS |
| Citation(s) |
22280838 |
| Submission date |
May 02, 2011 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Wusheng Yan |
| E-mail(s) |
yanw@mail.nih.gov
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| Organization name |
NCI
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| Street address |
8717 Grovemont Circle
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| City |
Gaithersburg |
| ZIP/Postal code |
20877 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (45)
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| Relations |
| BioProject |
PRJNA140407 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE29001_RAW.tar |
98.0 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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