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Series GSE29008 Query DataSets for GSE29008
Status Public on Jan 06, 2012
Title Human colon epithelial cells treated with Clostridium difficile Toxins A and B
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Toxin A and B from Clostridium difficile are the primary virulence factors in Clostridium difficile disease. The changes in gene transcription of human colon epithelial cells were investigated in vitro in order to better understand the many effects of both toxins.
 
Overall design HCT-8 cells were treated with 100 ng/ml of either Toxin A or B (TcdA or TcdB). RNA was isolated 2, 6, and 24 hours after addition of toxin from untreated and toxin-treated cells.
 
Contributor(s) D'Auria KM, Donato GM, Gray MC, Kolling GL, Warren CA, Papin JA, Hewlett EL
Citation(s) 22225989
Submission date May 02, 2011
Last update date Mar 25, 2019
Contact name Kevin Michael D'Auria
E-mail(s) kd3jd@virginia.edu
Organization name University of Virginia
Department Biomedical Engineering
Street address 415 Lane Road, Room 2041
City Charlottesville
State/province VA
ZIP/Postal code 22903
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (20)
GSM718715 Hct8-Control-2hr-1
GSM718716 Hct8-Control-2hr-2
GSM718717 Hct8-TcdA-2hr-1
Relations
BioProject PRJNA140459

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE29008_RAW.tar 91.3 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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