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Status |
Public on Dec 10, 2017 |
Title |
Identification of genes expressed by spinal cord neurons after axotomy and during axon regeneration |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
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Summary |
Abstract to follow Keywords: Regeneration, CNS, neuron, spinal, axon, SCI, axotomy
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Overall design |
7 regenerating (Reg), 7 non regenerating (NonReg) and 3 traced, not axotomised (NonAxot) samples of spinal neurons obtained by laser microdissection.
7 rats provided regenerating (Reg) and non-regenerating (NonReg) neurons, allowing within-animal comparison to identify regeneration-associated genes.
3 rats provided traced neurons (NonAxot), allowing between-animal comparison between traced and non-regenerating neurons to identify axotomy-related genes.
Each sample, 1000 laser captured, retrogradely labeled spinal cord neurons.
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Contributor(s) |
Moon LD, Bunge MB, Gage FH, Bixby J, Petito CK, Torres J, Lemmon V, van Kesteren R |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
Submission date |
Jul 12, 2005 |
Last update date |
Dec 10, 2017 |
Contact name |
Lawrence DF Moon |
E-mail(s) |
lawrence.moon@kcl.ac.uk
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Organization name |
King's College London
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Department |
Wolfson Centre for Age-Related Diseases
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Lab |
Moon team
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Street address |
16 - 18 Newcomen Street
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City |
London |
ZIP/Postal code |
SE11UL |
Country |
United Kingdom |
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Platforms (1) |
GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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Samples (17)
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Relations |
BioProject |
PRJNA92617 |
Supplementary file |
Size |
Download |
File type/resource |
GSE2925_RAW.tar |
77.8 Mb |
(http)(custom) |
TAR (of CEL) |
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