|
| Status |
Public on May 16, 2011 |
| Title |
Effect of endoglin loss on embryoid bodies |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of embryonic sten cell-derived embryoid bodies following endoglin knock out. Loss of endoglin leads to profound reduction of key hematopoietic regulators including SCL, LMO2, Gata2, and TGF-β signaling molecule ALK-1. Results provide insight into molecular mechanisms underlying hemangioblast and primitive hematopoietic development.
|
| |
|
| Overall design |
Total RNA obtained from differentiated day 3 EBs of endoglin knock out ES cells were compared to wild type E14 control ES cells.
|
| |
|
| Contributor(s) |
Zhang L, Perlingeiro R |
| Citation(s) |
21602526 |
| Submission date |
May 15, 2011 |
| Last update date |
Jan 18, 2013 |
| Contact name |
Rita Perlingeiro |
| E-mail(s) |
perli032@umn.edu
|
| Organization name |
University of Minnesota
|
| Department |
Medicine
|
| Lab |
Perlingeiro Lab
|
| Street address |
312 Church ST SE; NHH 4-124
|
| City |
Minneapolis |
| State/province |
MN |
| ZIP/Postal code |
55455 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6105 |
Illumina mouse-6 v1.1 expression beadchip |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA138629 |
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