NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE29615 Query DataSets for GSE29615
Status Public on Jul 10, 2011
Title Time Course of Young Adults Vaccinated with Influenza LAIV Vaccine during 2008/09 Flu Season
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology.
Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivated influenza (TIV) and live attenuated influenza (LAIV) vaccination in humans, and to identify early gene signatures that predict the magnitude of the antibody responses to influenza vaccination.
 
Overall design During the 2008 influenza season, healthy adults were vaccinated with LAIV (28 vaccinees), and blood samples isolated at days 0, 3, 7 post-vaccination. Microarrays were performed using total RNA extracted from the peripheral blood mononuclear cells of vaccinees.
 
Contributor(s) Nakaya HI, Pulendran B
Citation(s) 21743478
Submission date May 29, 2011
Last update date Feb 25, 2021
Contact name Helder I. Nakaya
E-mail(s) hnakaya@usp.br
Phone +551126481130
Organization name Universidade de São Paulo
Lab csbiology.com
Street address AVENIDA PROFESSOR LINEU PRESTES, 580, Block 17
City SÃO PAULO
State/province SÃO PAULO
ZIP/Postal code 05508000
Country Brazil
 
Platforms (1)
GPL13158 [HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate
Samples (83)
GSM733843 2008 LAIV subject ID 1 at D0 post-vaccination
GSM733844 2008 LAIV subject ID 1 at D3 post-vaccination
GSM733845 2008 LAIV subject ID 1 at D7 post-vaccination
This SubSeries is part of SuperSeries:
GSE29619 Systems biology of vaccination for seasonal influenza in humans
Relations
BioProject PRJNA153823

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE29615_RAW.tar 203.2 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap