|
| Status |
Public on Mar 31, 2012 |
| Title |
p53-dependent transcription program in HepG2 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
In order to obtain a global picture regarding regulation of p53 in liver cells we used HepG2 hepatoma cells.We created two isogenic sub-cultures of HepG2 cells with altered expression of p53.
HepG2 cells were infected with a retroviral vector harboring either small-hairpin RNA targeting p53 (termed HepG2sh-p53) or a non relevant small-hairpin RNA (termed HepG2sh-con).
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| |
|
| Overall design |
Cells were treated with two different p53 stimulators - Nutlin and AICAR
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| |
|
| Contributor(s) |
Goldstein I, Rotter V |
| Citation(s) |
23054612, 24280180 |
| Submission date |
Jun 22, 2011 |
| Last update date |
Aug 01, 2019 |
| Contact name |
Ido Goldstein |
| E-mail(s) |
goldstein.ido@gmail.com
|
| Organization name |
The Weizmann Institute of Science
|
| Street address |
POB 26
|
| City |
Rehovot |
| ZIP/Postal code |
76100 |
| Country |
Israel |
| |
|
| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA143835 |
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