|
| Status |
Public on Jun 01, 2012 |
| Title |
Clock rescue in the brain restores 12- and 24- hour rhythms in the liver |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Circadian profiling was performed in mouse livers from three different genotypes/treatments: Wildtype, Clock mutant, and brain-specific Clock rescue. Rescuing Clock specifically in the brain partially rescued robust circadian and harmonic rhythms.
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| |
|
| Overall design |
Samples were collected every 2 hours for 48 hours from 2-4 mice per time point; samples were pooled and analyzed using Affymetrix Mouse Exon arrays, analyzed at the gene level.
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| |
|
| Contributor(s) |
Hughes M, Hong H, Chong J, Takahashi J, Hogenesch J |
| Citation(s) |
22844252 |
| Submission date |
Jul 05, 2011 |
| Last update date |
Mar 06, 2018 |
| Contact name |
Michael Hughes |
| E-mail(s) |
michael.evan.hughes@gmail.com
|
| Organization name |
UPenn
|
| Street address |
421 Curie Bvd, Brb 835
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
|
| Samples (72)
|
|
| Relations |
| BioProject |
PRJNA143375 |
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