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| Status |
Public on Jul 03, 2013 |
| Title |
Gene expression profile in the diaphragm following contractile inactivity during thoracic surgery |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Recent work revealed the development of marked diaphragm muscle fiber weakness during two hours of thoracic surgery. This loss of muscle fiber function was not part of a generalized muscle weakness as function of the non-respiratory latissimus dorsi muscle was preserved. To disentangle the molecular processes that might underlie the development of diaphragm muscle fiber weakness during thoracic surgery we studied changes in the gene expression profile.
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| |
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| Overall design |
Analyzed were diaphragm samples at t0 vs t2 and latissimus dorsi at t0 vs t2. In total 8 Diaphragm samples and 6 latissimus dorsi samples were analyzed.
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| Contributor(s) |
Ottenheijm CA |
| Citation(s) |
21941608 |
| Submission date |
Jul 14, 2011 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Daoud Sie |
| E-mail(s) |
d.sie@vumc.nl
|
| Phone |
+31 20 4442428
|
| Organization name |
Vrije Universiteit Medical Center
|
| Department |
Pathology
|
| Lab |
Microarray Core Facility
|
| Street address |
De Boelelaan 1117
|
| City |
Amsterdam |
| ZIP/Postal code |
1081 HV |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
|
| Samples (9)
|
| GSM760562 |
Diaphragm_t=o_A1 vs Diaphragm_t=2_A2 |
| GSM760563 |
Diaphragm_t=2_A2 vs Diaphragm_ t=0_A1 |
| GSM760564 |
Diaphragm_t=o_B1 vs Diaphragm_t=2_B2 |
| GSM760565 |
Diaphragm_t=2_B2 vs Diaphragm_ t=0_B1 |
| GSM760566 |
Diaphragm_t=o_C1 vs Diaphragm_t=2_C2 |
| GSM760567 |
Diaphragm_t=o_D1 vs Diaphragm_t=2_D2 |
| GSM760568 |
Latissimus dorsi_t=o_X1 vs Latissimus dorsi_t=2_X2 |
| GSM760569 |
Latissimus dorsi_t=o_Y1 vs Latissimus dorsi_t=2_Y2 |
| GSM760570 |
Latissimus dorsi_t=o_Z1 vs Latissimus dorsi_t=2_Z2 |
|
| Relations |
| BioProject |
PRJNA144609 |
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