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| Status |
Public on Nov 07, 2011 |
| Title |
RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice. |
| Organisms |
Mus musculus; Heterocephalus glaber |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal was to find genes which are differentially expressed between the naked mole-rat (Heterocephalus glaber) and the wild-type mice liver tissue. The genes which are most differentially expressed may provide a clue for the remarkable differences between naked mole-rat and mouse in terms of longevity, cancer resistance and adaptation to subterranean environments.
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| Overall design |
Analysis of 2 mRNA samples, one pooled from 3 wild-type mice liver tissue and another pooled from 3 naked mole-rat liver tissue.
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| Contributor(s) |
Yu C, Li Y, Holmes A, Szafranski K, Faulkes CG, Coen CW, Buffenstein R, Platzer M, de Magalhães JP, Church GM |
| Citation(s) |
22073188 |
| Submission date |
Jul 18, 2011 |
| Last update date |
May 15, 2019 |
| Contact name |
Yang Li |
| E-mail(s) |
yang.li@well.ox.ac.uk
|
| Organization name |
University of Oxford
|
| Department |
Nuffield Department of Medicine
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| Street address |
3 Fettlers House, Walton Wells Road
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| City |
Oxford |
| ZIP/Postal code |
OX2 6GE |
| Country |
United Kingdom |
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| Platforms (2) |
| GPL9185 |
Illumina Genome Analyzer (Mus musculus) |
| GPL13940 |
Illumina Genome Analyzer (Heterocephalus glaber) |
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| Samples (2) |
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| Relations |
| SRA |
SRP007512 |
| BioProject |
PRJNA144103 |
