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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Dec 01, 2011 |
| Title |
A key role for Mbd3 in 5-hydroxymethylcytosine-dependent gene regulation in embryonic stem cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To identify functional interactions among six chromatin regulators with key roles in embryonic stem cells, we examined gene expression changes in mouse ES cells with single and pair-wise combinations of knockdowns for those factors, along with control (EGFP) KDs.
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| Overall design |
Effects on gene expression of RNAi-mediated knockdown of combinations of chromatin regulators. KDs were performed in duplicate for each combination for 48 hours.
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| Contributor(s) |
Fazzio TG |
| Citation(s) |
22196727 |
| Submission date |
Jul 28, 2011 |
| Last update date |
Jan 12, 2017 |
| Contact name |
Thomas G. Fazzio |
| E-mail(s) |
thomas.fazzio@umassmed.edu
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| Phone |
508-856-6014
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| Organization name |
University of Massachusetts Medical School
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| Department |
Program in Gene Function and Expression
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| Street address |
LRB 519, 364 Plantation Street
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| City |
Worcester |
| State/province |
MA |
| ZIP/Postal code |
01605 |
| Country |
USA |
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| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
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| Samples (44)
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| GSM768328 |
p400Mbd3 KD, replicate B |
| GSM768329 |
p400Suz12 KD, replicate A |
| GSM768330 |
p400Suz12 KD, replicate B |
| GSM768331 |
p400Ash2l KD, replicate A |
| GSM768332 |
p400Ash2l KD, replicate B |
| GSM768333 |
p400 KD, replicate A |
| GSM768334 |
p400 KD, replicate B |
| GSM768335 |
p400Tip60 KD, replicate A |
| GSM768336 |
p400Tip60 KD, replicate B |
| GSM768337 |
p400Brg1 KD, replicate A |
| GSM768338 |
p400Brg1 KD, replicate B |
| GSM768339 |
Tip60Mbd3 KD, replicate A |
| GSM768340 |
Tip60Mbd3 KD, replicate B |
| GSM768341 |
Tip60Suz12 KD, replicate A |
| GSM768342 |
Tip60Suz12 KD, replicate B |
| GSM768343 |
Tip60Ash2l KD, replicate A |
| GSM768344 |
Tip60Ash2l KD, replicate B |
| GSM768345 |
Tip60 KD, replicate A |
| GSM768346 |
Tip60 KD, replicate B |
| GSM768347 |
Tip60Brg1 KD, replicate A |
| GSM768348 |
Tip60Brg1 KD, replicate B |
| GSM768349 |
Brg1Mbd3 KD, replicate A |
| GSM768350 |
Brg1Mbd3 KD, replicate B |
| GSM768351 |
Brg1Suz12 KD, replicate A |
| GSM768352 |
Brg1Suz12 KD, replicate B |
| GSM768353 |
Brg1Ash2l KD, replicate A |
| GSM768354 |
Brg1Ash2l KD, replicate B |
| GSM768355 |
Brg1 KD, replicate A |
| GSM768356 |
Brg1 KD, replicate B |
| GSM768357 |
Mbd3 KD, replicate A |
| GSM768358 |
Mbd3 KD, replicate B |
| GSM768359 |
Mbd3Suz12 KD, replicate A |
| GSM768360 |
Mbd3Suz12 KD, replicate B |
| GSM768361 |
Mbd3Ash2l KD, replicate A |
| GSM768362 |
Mbd3Ash2l KD, replicate B |
| GSM768363 |
Suz12 KD, replicate A |
| GSM768364 |
Suz12 KD, replicate B |
| GSM768365 |
Suz12Ash2l KD, replicate A |
| GSM768366 |
Suz12Ash2l KD, replicate B |
| GSM768367 |
Ash2l KD, replicate A |
| GSM768368 |
Ash2l KD, replicate B |
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| Relations |
| BioProject |
PRJNA146333 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE31008_RAW.tar |
95.9 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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