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| Status |
Public on Aug 03, 2011 |
| Title |
Integrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells [ChIP-Seq data] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We profiled two repressive histone modifications (H3K9m3 and H3K27m3) using ChIP-Seq in normal urothelial cells and cell lines representing non-invasive and invasive tumors.
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| Overall design |
Two bladder cancer cell lines (RT112 and EJ/T24 from ATCC) and normal human urothelial (NHU) cells were treated according to standard ChIP-Seq protocols using antibodies against the histone modifications H3K9m3 and H3K27m3 (from Millipore). The sequencing reads were mapped against the human genome (GRCh37/hg19).
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| |
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| Contributor(s) |
Dudziec E, Gogol-Döring A, Guy V, Chen W, Catto J |
| Citation(s) |
22412920 |
| Submission date |
Aug 02, 2011 |
| Last update date |
May 15, 2019 |
| Contact name |
Andreas Gogol-Döring |
| E-mail(s) |
andreas.gogol-doering@mni.thm.de
|
| Organization name |
Technische Hochschule MIttelhessen
|
| Department |
MNI
|
| Street address |
Wiesenstraße 14
|
| City |
Gießen |
| ZIP/Postal code |
35390 |
| Country |
Germany |
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| Platforms (1) |
| GPL9052 |
Illumina Genome Analyzer (Homo sapiens) |
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| Samples (6)
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| Relations |
| SRA |
SRP007638 |
| BioProject |
PRJNA144937 |
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