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Status |
Public on Jun 13, 2012 |
Title |
The DNA methylomes of a newborn and a centenarian |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by high throughput sequencing
|
Summary |
We have developed Whole Genome Bisulfite Sequencing (WGBS) of a newborn and a centenarian to address the epigenetic drifts in human aging, which might be an alternative pathway to explain the age-associated alterations. In addition, we have analyzed the methylome of a middle-age donor (26 years).
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Overall design |
Examination of two DNA methylomes at the most extreme points of their lives to see differences that might contribute to explain the aged phenotype. The methylome of a middle-age donor (26 years) was also analyzed.
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Contributor(s) |
Holger H, Manel E |
Citation(s) |
22689993 |
Submission date |
Aug 08, 2011 |
Last update date |
May 15, 2019 |
Contact name |
Manel Esteller |
Organization name |
IDIBELL
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Department |
PEBC
|
Lab |
Cancer Epigenetics
|
Street address |
Hospital Duran i Reynals Av. Gran Via s/n km, 2.7
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City |
L'Hospitalet de Llobregat |
State/province |
Barcelona |
ZIP/Postal code |
08908 |
Country |
Spain |
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Platforms (2) |
GPL9052 |
Illumina Genome Analyzer (Homo sapiens) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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Samples (3) |
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Relations |
SRA |
SRP007820 |
BioProject |
PRJNA144837 |