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Series GSE31263 Query DataSets for GSE31263
Status Public on Jun 13, 2012
Title The DNA methylomes of a newborn and a centenarian
Organism Homo sapiens
Experiment type Methylation profiling by high throughput sequencing
Summary We have developed Whole Genome Bisulfite Sequencing (WGBS) of a newborn and a centenarian to address the epigenetic drifts in human aging, which might be an alternative pathway to explain the age-associated alterations. In addition, we have analyzed the methylome of a middle-age donor (26 years).
 
Overall design Examination of two DNA methylomes at the most extreme points of their lives to see differences that might contribute to explain the aged phenotype. The methylome of a middle-age donor (26 years) was also analyzed.
 
Contributor(s) Holger H, Manel E
Citation(s) 22689993
Submission date Aug 08, 2011
Last update date May 15, 2019
Contact name Manel Esteller
Organization name IDIBELL
Department PEBC
Lab Cancer Epigenetics
Street address Hospital Duran i Reynals Av. Gran Via s/n km, 2.7
City L'Hospitalet de Llobregat
State/province Barcelona
ZIP/Postal code 08908
Country Spain
 
Platforms (2)
GPL9052 Illumina Genome Analyzer (Homo sapiens)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (3)
GSM774849 103 year-old male Caucasian
GSM774850 newborn male Caucasian
GSM848927 middle-age donor
Relations
SRA SRP007820
BioProject PRJNA144837

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE31263_RAW.tar 202.9 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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