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Status |
Public on Aug 30, 2011 |
Title |
Mtb-mediated host transcriptional reponse is strain-specific |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
CDC1551 induced more vigorous immune response in murine bone marrow derived macrophage (BMM). In contrast, in HN878-infected cells, host transcriptional response was delayed but lasted longer. HN878 induced more genes involved in host lipid metabolism than CDC1551 did.
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Overall design |
Murine bone marrow derived macrophages were infected with M. tuberculosis CDC1551 or HN878 up to 24 h. Total RNA was processed for microarray and global gene expression was read.
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Contributor(s) |
Koo M |
Citation(s) |
22280836 |
Submission date |
Aug 29, 2011 |
Last update date |
Oct 31, 2019 |
Contact name |
Mi-Sun Koo |
E-mail(s) |
koomi@umdnj.edu
|
Phone |
9738543226
|
Fax |
972854322
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Organization name |
University of Medicine and Dentistry of New Jersey
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Department |
Public Health Research Institute
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Street address |
225 Warren Street, W250Q
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City |
Newark |
State/province |
NJ |
ZIP/Postal code |
07103 |
Country |
USA |
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Platforms (1) |
GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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Samples (18)
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Relations |
BioProject |
PRJNA145429 |