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Series GSE32693 Query DataSets for GSE32693
Status Public on Jan 01, 2013
Title Expression data of statin treated HUVEC cells transfected siRNA KLF2 or KLF4.
Organism Homo sapiens
Experiment type Expression profiling by array
Summary KLF2 and KLF4 are important transcriptional factors in endothelial cells, however their roles in statin treatment has not been elucidated. Here we report the comprehensive change of transcripts of statin treated HUVECs transfected with siRNA KLF2 or KLF4.
We used repeated microarray analysis of HUVECs treated with pitavastatin for 4hours. Before statin treatment, cells were transfected with siRNA KLF2 or KLF4.
 
Overall design HUVECs were used within the first 6 passages. For studies, HUVECs were cultivated in medium EGM2MV containing pitavastatin at a concentration of 1 micromolar.
 
Contributor(s) Maejima T, Kohro T, Kodama T, Wada Y
Citation(s) 24797675
Submission date Oct 07, 2011
Last update date Mar 25, 2019
Contact name Takahide Kohro
E-mail(s) kohro@lsbm.org
Phone 81-3-5452-5237
Organization name LSBM, RCAST
Street address
City 4-6-1, Komaba, Meguroku
State/province Tokyo
ZIP/Postal code 153-8904
Country Japan
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (4)
GSM812374 Endothelial Cells siRNA KLF2
GSM812375 Endothelial Cells siRNA KLF2 rep2
GSM812376 Endothelial Cells siRNA KLF4
Relations
BioProject PRJNA146895

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE32693_RAW.tar 33.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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