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Series GSE3290 Query DataSets for GSE3290
Status Public on Sep 13, 2005
Title Expression profiling in perinatal Ductus Arteriosus (DA) and Aorta (Ao).
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary Compared the gene expression profiles of two contiguous vessels pre and post - birth, namely the Ductus Arteriosus (DA), committed to become a fibrous ligament, and the Aorta (Ao), which conversely takes on a permanent activity. The effect of artificially enhanced O2 tension was analyzed in DA in the pre-birth condition.
Keywords: Comparison gene expression
 
Overall design 5 experimental conditions:
1) DA of 19 days post coitum (dpc) fetuses (DA19)
2) DA of 19 dpc fetuses from dams kept at 100% O2 for three hours prior to cesarian section (DA 19 O2)
3) DA of 3 hrs newborn rats (DA3)
4) Ao of 19 dpc fetuses (Ao19)
5) Ao of 3 hrs newborn rats (Ao3)

5 total hybridizations

Hybridization design:

Multiple comparisons among pre-birth DA, post-birth DA, pre-birth Ao and post-birth Ao to identify specific markers for each of these conditions; triple comparison between artificially oxygenated pre-birth DA and post-birth DA using normal prebirth-DA as reference sample; comparison between pre-birth DA and post-birth DA (supplementary data, table 2); Comparison between pre-birth Ao and post-birth Ao

 
Contributor(s) Costa M, Barogi S, Socci ND, Angeloni D, Maffei M, Baragatti B, Chiellini C, Grasso E, Coceani F
Citation(s) 16418320
Submission date Sep 11, 2005
Last update date Feb 21, 2017
Contact name Flavio Coceani
E-mail(s) coceani@sssup.it
Phone +39 050 883327
Fax +39 050 883215
Organization name Scuola Superiore S. Anna
Department Settore di Scienze Mediche
Street address Piazza Martiri della Libertà, 33
City Pisa
ZIP/Postal code 56127
Country Italy
 
Platforms (3)
GPL85 [RG_U34A] Affymetrix Rat Genome U34 Array
GPL86 [RG_U34B] Affymetrix Rat Genome U34 Array
GPL87 [RG_U34C] Affymetrix Rat Genome U34 Array
Samples (15)
GSM73652 Aorta 19 days post coitum
GSM73689 Aorta 3 hours post coitum
GSM73790 Ductus Arteriosus 19 days post coitum
Relations
BioProject PRJNA92793

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary data files not provided

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