|
| Status |
Public on Oct 20, 2011 |
| Title |
Identification of the altered transcripts in the NMF291–/– cerebellum by exon array. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The U2 snRNA is a basal component of the major spliceosome, which is responsible for >90% human pre-mRNA splicing. A 5-nucleotide deletion in one of the mouse U2 snRNA genes (Rnu2-8) causes cerebellar granule cell degeneration in the NMF291 mouse mutant strain. To identify the altered transcripts in the NMF291–/– cerebellum, we interograted Affy. mouse 1.0 ST Exon arrays with total RNAs from three postnatal-30-day (P30) wild type and three NMF291–/– cerebella.
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| |
|
| Overall design |
Affy. mouse 1.0 ST Exon arrays were hybridized with total RNAs derived from three P30 female wild type and NMF291–/– mice (biological replicates).
|
| |
|
| Contributor(s) |
Jia Y, Ackerman S |
| Citation(s) |
22265417 |
| Submission date |
Oct 19, 2011 |
| Last update date |
Mar 06, 2018 |
| Contact name |
Pierre de la Grange |
| E-mail(s) |
pierre.delagrange@genosplice.com
|
| Organization name |
GenoSplice technology
|
| Department |
Paris Biotech Santé
|
| Street address |
29, rue du Faubourg Saint-Jacques
|
| City |
Paris |
| ZIP/Postal code |
75014 |
| Country |
France |
| |
|
| Platforms (2) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
| GPL6193 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [probe set (exon) version] |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA149473 |
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