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Status |
Public on Nov 05, 2011 |
Title |
Meta-analysis of Clear Cell Renal Cell Carcinoma Gene Expression Defines a Variant Subgroup and Identifies Gender Influences on Tumor Biology |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array Third-party reanalysis
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Summary |
Clear cell renal cell carcinoma comprises two dominant subtypes, ccA and ccB, with gender disparity providing additional disease information. A third minor subgroup has distinct expression profiles consistent with von Hippel-Lindau wild type status and displays variant histology features.
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Overall design |
44 new tumor samples and six large, publicly available, ccRCC gene expression databases were identified that cumulatively provided data for 480 tumors for metaanalysis via meta-array compilation.
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Contributor(s) |
Brannon AR, Haake SM, Hacker KE, Pruthi R, Wallen E, Nielsen ME, Rathmell WK |
Citation(s) |
22030119 |
Submission date |
Oct 19, 2011 |
Last update date |
Feb 22, 2018 |
Contact name |
Kimryn Rathmell |
E-mail(s) |
kimryn.rathmell@vanderbilt.edu
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Organization name |
Vanderbilt
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Department |
Medicine
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Lab |
Rathmell
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Street address |
2220 Pierce Ave
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City |
Nashville |
State/province |
TN |
ZIP/Postal code |
37232 |
Country |
USA |
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Platforms (1) |
GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
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Samples (44)
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BioProject |
PRJNA149335 |