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Series GSE33159 Query DataSets for GSE33159
Status Public on Oct 22, 2011
Title Identification of TDP-43 and FUS mRNA targets and pathways in the cytoplasmic compartment of motoneuronal NSC-34 cells
Organism Mus musculus
Experiment type Other
Summary We performed RNA immunoprecipitation (IP) and microarray (RIP-chip) analyses to identify and compare the biological mRNA targets of two RNA-binding proteins (RBP), TDP-43 and FUS, associated to cytoplasmic ribonucleoprotein (RNP) complexes of motoneuronal NSC-34 cells with the final aim to unravel their role in mRNA transport, stability, and translation in neuronal cells.
 
Overall design To identify the transcripts contained and bound in the isolated RNP complexes, a chip analysis was performed using the recovered mRNAs from triplicate experimantal RIP samples (TDP-43-IP samples, the FUS-IP samples and the control IgG-IP sample).
 
Contributor(s) Ratti A, Colombrita C, Onesto E
Citation(s) 22427648
Submission date Oct 21, 2011
Last update date Jun 14, 2018
Contact name Claudia Colombrita
Organization name IRCCS Istituto Auxologico Italiano
Street address Via Zucchi, 18
City Cusano milanino
ZIP/Postal code 20095
Country Italy
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (12)
GSM821072 RNPs TDP-43-IP rep1
GSM821073 RNPs TDP-43-IP rep2
GSM821074 RNPs TDP-43-IP rep3
Relations
BioProject PRJNA149179

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE33159_RAW.tar 3.1 Mb (http)(custom) TAR
GSE33159_non_normalized.txt.gz 2.1 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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