|
| Status |
Public on Dec 06, 2011 |
| Title |
The effect of androgen deprivation on human prostate xenograft tumor LuCaP35 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Androgen deprivation is a standard of care front-line therapy for human prostate cancer, however, majority of patients will eventally develop resistance to androgen deprivation. In this study, using a human prostate cancer xenograft model -LuCaP35, we examiend the gene expression changes after castration.
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| |
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| Overall design |
We compare the gene expression of 5 LuCaP35 xenografts from non-treated mice (Control), and 5 androgen-deprived LuCaP35 xenografts from castrated mice (Castration).
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| Contributor(s) |
Sun Y, Gao W, Settleman J, Johnson L |
| Citation(s) |
22108827 |
| Submission date |
Oct 28, 2011 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Yuting Sun |
| Organization name |
Genentech
|
| Department |
Research Oncology
|
| Street address |
1 DNA way
|
| City |
South San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94080 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (10)
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| Relations |
| BioProject |
PRJNA149301 |
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