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| Status |
Public on Dec 06, 2011 |
| Title |
Gene expression profiling of mouse prostate stem cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The mouse prostate tissue exhibits strong power of regeneration, indicating the exisistence of prostate stem cells. Previously we showed that a single mouse prostate cells defined by Lin-CD44+CD133+Sca-1+CD117+ phenotype can generate a prostate after transplantation in vivo.
In this study, we compared gene expression profiles of mouse prostate stem cells ( Lin-CD44+CD133+Sca-1+CD117+) and prostate non-stem cells (Lin-CD44-CD133-Sca-1-CD117-).
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| Overall design |
Primary mouse prostate cells were isolated from BL6 mice. Lin-CD44+CD133+Sca-1+CD117+ and Lin-CD44-CD133-Sca-1-CD117- cells were sorted via FACS, and microarray was performed to compare gene expressions between the two groups of cells.
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| Contributor(s) |
Sun Y, Gao W, Settleman J, Johnson L |
| Citation(s) |
22108827 |
| Submission date |
Oct 28, 2011 |
| Last update date |
Jan 12, 2017 |
| Contact name |
Yuting Sun |
| Organization name |
Genentech
|
| Department |
Research Oncology
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| Street address |
1 DNA way
|
| City |
South San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94080 |
| Country |
USA |
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| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA149303 |
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