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Series GSE33451 Query DataSets for GSE33451
Status Public on Nov 05, 2011
Title Genome-wide analysis of gene transcription in myocardium of mice transgenically expressing human cardiolipin synthase 1 (hCLS1) in cardiac tissue
Organism Mus musculus
Experiment type Expression profiling by array
Summary Analysis of the transcriptome of cardiac tissue from mice transgenically expressing human cardiolipin synthesis. The hypothesis tested was that cardiac specific transgenic expression of cardiolipin synthase alters myocardial lipidomic flux resulting in compensatory metabolic gene transcriptional changes that will attenuate pathological environmental and dietary insults on bioenergetics.
 
Overall design Total RNA obtained from cardiac tissue from transgenic cardiac specific expressing human cardiolipin synthase 1 (hCLS1) mouse model at 4 months of age compared to wildtype littermates
 
Contributor(s) Kiebish MA, Gross RW, Han X
Citation(s) 22584571
Submission date Nov 03, 2011
Last update date Jun 14, 2018
Contact name Michael Andrew Kiebish
E-mail(s) kiebish@wustl.edu
Phone 314-362-2229
Fax 314-362-1402
Organization name Washington University School of Medicine
Department Internal Medicine
Lab Richard W. Gross
Street address 660 South Euclid Avenue, Campus Box 8020
City Saint Louis
State/province MO
ZIP/Postal code 63110
Country USA
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (8)
GSM827096 Heart 4 month old WT rep1 (mouse 5976)
GSM827097 Heart 4 month old WT rep2 (mouse 5977)
GSM827098 Heart 4 month old WT rep3 (mouse 5966)
Relations
BioProject PRJNA148711

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE33451_RAW.tar 3.1 Mb (http)(custom) TAR
GSE33451_non-normalized.txt.gz 1.5 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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