 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Nov 20, 2011 |
| Title |
S100A8 treatment on gene expression of human umbilical vascular endothelial cells. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Previous studies showed that S100A8 and S100A9 are involved in neovascularization as well as in tumor development. At high concentrations, S100A8 and S100A9 cause inflammatory response or apoptosis mediated damage in vascular endothelial cells. But the effect of low concentrations of such proteins on endothelial cells remains unknown. This assay was performed to screen for genes that are involved in the response of Human Unbilican Vascular Endothelial Cells to low concentrations of S100A8.
|
| |
|
| Overall design |
Human Umblical Vascular Endothelial Cells (HUVEC) were cultuered and treated with 10ug/mL S100A8 proteins for 4 or 24 hours. Gene profiling was carried out using two-color microarray.
Two-condition experiment, S100A8 treatment vs. non-treatment. Two time points: 4 hours and 24 hours. Biological replicates at each time point: 3 control replicates, 3 treatment replicates.
|
| |
|
| Contributor(s) |
Yang L, Jia C, Wang Y |
| Citation(s) |
22685372 |
| Submission date |
Nov 17, 2011 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Yiqiang Wang |
| E-mail(s) |
yiqiangwang99@hotmail.com
|
| Phone |
86-512-67780780
|
| Organization name |
Xiamen University
|
| Street address |
2000 East Xiangan Road
|
| City |
Xiamen |
| ZIP/Postal code |
361101 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA148379 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE33768_RAW.tar |
52.0 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
|
|
|
|
 |
Less...
More...