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Series GSE33995 Query DataSets for GSE33995
Status Public on Aug 31, 2012
Title The effect of pertussis toxin on lung airway gene expression during B. pertussis infection in mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary Genome-wide expression analysis of mouse lung responses to Bordetella pertussis infection and the effects of pertussis toxin
Overall design Total lung RNA from wild-type and pertussis toxin-defficient B. pertussis-infected mice at two and four days post inoculation compared to control, mock-infected mice. Seven-week old female BALB/c mice were intranasally inoculated with 1 x 106 CFU WT B. pertussis (Tohama I), 1 x 106 CFU ΔPT (WT carrying a PT deletion), or 30 x 106 CFU of the ΔPT strain. Whole lung tissue was collected from mice sacrificed at 2 and 4 days post inoculation (n = 3 per group per time point). Control mice were inoculated with PBS and sacrificed 2 days post inoculation (n = 2).
Contributor(s) Connelly CE, Sun Y, Carbonetti NH
Citation(s) 23027529
Submission date Nov 29, 2011
Last update date Jun 14, 2018
Contact name Nicholas Carbonetti
Organization name University of Maryland Baltimore
Department Microbiology and Immunology
Lab Carbonetti Lab
Street address 685 W. Baltimore St. HSF I-380
City Baltimore
State/province MD
ZIP/Postal code 21201
Country USA
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (20)
GSM840140 WT d2 a
GSM840141 WT d2 b
GSM840142 WT d2 c
BioProject PRJNA150639

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE33995_RAW.tar 3.1 Mb (http)(custom) TAR
GSE33995_non-normalized.txt.gz 2.0 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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