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| Status |
Public on Dec 02, 2011 |
| Title |
Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells revels potential intervention targets for plasma-cell neoplasia |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We extracted nascent plasma cell tumor (PCT) cells from within inflammatory granulomas (OG) isolated from intraperitoneal pristane-injected BALB/c.iMyc Eμ mice at five different time points during tumor progression. We used laser capture micro-dissection to collect incipient PCT cells and analyzed their global gene expression on Affymetrix Mouse Genome 430A microarrays. Two independent studies were performed with different sets of mice
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| Overall design |
RNA was extracted from both laser capture samples and whole tissue sections at 5 different times after tumor initiation: 7 days, 17 days, 33 days, 49/46 days and 104/105 days in two independent experiments, studies 1 and 2
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| Contributor(s) |
LeGrand J, Park E, Wang H, Gupta S, Owens JD Jr, Nelson PJ, DuBois W, Bair T, Janz S, Mushinski JF |
| Citation(s) |
22147894 |
| Submission date |
Dec 01, 2011 |
| Last update date |
May 04, 2018 |
| Contact name |
Thomas B Bair |
| E-mail(s) |
iihg-bioinformatics@uiowa.edu
|
| Organization name |
University of Iowa
|
| Street address |
335 EMRB
|
| City |
Iowa City |
| State/province |
IA |
| ZIP/Postal code |
52242 |
| Country |
USA |
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| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
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| Samples (82)
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| Relations |
| BioProject |
PRJNA150005 |
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