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Series GSE3414 Query DataSets for GSE3414
Status Public on May 01, 2006
Title Immune Response to Nippostrongylus brasiliensis in the mouse lung
Organism Mus musculus
Experiment type Expression profiling by array
Summary The goal of this experiment was to examine the innate immune response to helminth infection in the lung. Hookworms (like many other helminths) use an obligate migration pathway through the lung. Their infection has been characterized in the gut in detail, but early immune responses in the lung have not been fully characterized.
Keywords: Time Course
Overall design SCID mice were used to examine the innate immune response. SCID mice have no functional B or T cells but a fully functional innate immune system. SCID and WT mice were infected with 500 L3 stage infectious Nippostrongylus brasiliensis SC and their lungs were removed at days 2,3,4,8 and 12 post infection.
Contributor(s) Reece JJ, Siracusa MC, Scott AL
Citation(s) 16926388
Submission date Oct 04, 2005
Last update date Feb 11, 2019
Contact name Joshua J Reece
Organization name Johns Hopkins University BSPH
Department MMI
Lab Lab of Alan Scott
Street address 615 N. Wolfe Street
City Baltimore
State/province MD
ZIP/Postal code 21205
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (36)
GSM76963 mouselung_wt_control_rep01
GSM76964 mouselung_wt_control_rep02
GSM76965 mouselung_wt_control_rep03
BioProject PRJNA93439

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE3414_RAW.tar 215.8 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file

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