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Series GSE3425 Query DataSets for GSE3425
Status Public on Nov 02, 2005
Title Silencing of microRNAs in vivo with "antagomirs"
Organism Mus musculus
Experiment type Expression profiling by array
Summary Using a novel class of chemically-engineered oligonucleotides, termed "antagomirs", we studied the biological significance of silencing miR-122 in the liver of mice at the mRNA level
Keywords: treatment response
Overall design Mice were injected on three subsequent days with antagomir-122 or scrambled control (mm-antagomir-122), respectively; 80mg/kg bodyweight/day. 24 hrs after the last treatment, mice were sacrificed and total RNA isolated from the livers. RNA from three mice was pooled and used for generation of biotin-labelled cRNA.
Contributor(s) Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M
Citation(s) 16258535
Submission date Oct 07, 2005
Last update date Feb 11, 2019
Contact name Markus Stoffel
Phone 212-327-8797
Fax 212-327-7997
Organization name Rockefeller University
Department Laboratory of Metabolic Diseases
Street address 1230 York Avenue
City New York
State/province NY
ZIP/Postal code 10021
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (2)
GSM77216 antagomir122
GSM77217 scrambled antagomir122 (mm-antagomir122)
BioProject PRJNA93459

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE3425_RAW.tar 13.1 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file

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