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Status |
Public on Jul 11, 2012 |
Title |
Transcriptional Alterations in Skeletal Muscle Following Desmin Deletion |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Desmin is a cytoskeletal protein in muscle involved in integrating cellular space and transmitting forces. In this study we sought to determine the effects of desmin deletion on skeletal muscle at the transcriptional level across many pathways of muscle physiology.
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Overall design |
RNA was isolated from the TA muscle of mice of two genotypes (wildtype (WT) and desmin knockout (KO)) and two ages (7-9 weeks (Adult) and 12-14 months (Aged)). Numbers per group are as follows: WT_Adult (5), WT_Aged (5), KO_Adult (5), KO_Aged (4).
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Contributor(s) |
Meyer GA, Lieber RL |
Citation(s) |
22442138 |
Submission date |
Dec 12, 2011 |
Last update date |
May 04, 2018 |
Contact name |
Gretchen Meyer |
Organization name |
University of California San Diego
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Department |
Bioengineering
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Street address |
9500 Gilman Dr
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City |
La Jolla |
State/province |
CA |
ZIP/Postal code |
92122 |
Country |
USA |
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Platforms (1) |
GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
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Samples (19)
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Relations |
BioProject |
PRJNA149583 |