|
| Status |
Public on Sep 04, 2012 |
| Title |
The genomic architecture of host whole blood transcriptional response to malaria infection |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of the effect of malaria infection on whole blood gene expression and uncovering regulatory effects using eQTL analysis. Testing for relashionships between genotype, expression and malaria phenotypes.
|
| |
|
| Overall design |
We generated whole blood gene expression profiles and genotypes from 155 West-African children including 94 cases undergoing the symptomatic phase of blood-stage Plasmodium falciparum infection and 61 age-matched controls. PCA, analysis of covariance and eQTL analysis were performed on the data.
|
| |
|
| Contributor(s) |
Idaghdour Y, Awadalla P |
| Citation(s) |
22949651 |
| Submission date |
Dec 13, 2011 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Youssef Idaghdour |
| E-mail(s) |
youcarolina@gmail.com
|
| Organization name |
NCSU
|
| Department |
Genetics
|
| Lab |
Gibson
|
| Street address |
Gardner Hall NCSU Campus
|
| City |
Raleigh |
| State/province |
NC |
| ZIP/Postal code |
27695 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (155)
|
|
| Relations |
| BioProject |
PRJNA149639 |
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