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Series GSE34517 Query DataSets for GSE34517
Status Public on Oct 02, 2012
Title Cigarette smoking alters mRNA expression in human alveolar macrophages
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Alveolar macrophages from never smokers and active smokers were isolated by bronchoalveolar lavage and gene expression was measured. Chronic cigarette smoke exposure, as occurs in smoker's lungs, leads to significant changes in gene expression. Of note, RNA was isolated immediately following bronchoscopy. Alveolar macrophage levels were >95%.
 
Overall design 4 never smokers and 4 active smokers were recruited for the study. After bronchoalveolar lavage and RNA isolation, gene expression was measured using Affymetrix Human Exon 1.0 ST arrays.
 
Contributor(s) Monick MM, Bair T
Citation(s) 22952876, 24668803
Submission date Dec 16, 2011
Last update date Feb 18, 2019
Contact name Thomas B Bair
E-mail(s) iihg-bioinformatics@uiowa.edu
Organization name University of Iowa
Street address 335 EMRB
City Iowa City
State/province IA
ZIP/Postal code 52242
Country USA
 
Platforms (1)
GPL5175 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version]
Samples (8)
GSM850459 Non-smoker 1
GSM850460 Non-smoker 2
GSM850461 Non-smoker 3
Relations
BioProject PRJNA151409

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE34517_RAW.tar 173.3 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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