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| Status |
Public on Dec 28, 2011 |
| Title |
Characterization of exosomes from highly metastatic pancreatic adenocarcinoma line: ASML and a CD44v kd of ASML based on their miRNA content |
| Platform organisms |
Homo sapiens; Mus musculus; Rattus norvegicus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; human gammaherpesvirus 4; JC polyomavirus; Human immunodeficiency virus 1; Murid gammaherpesvirus 4; Human gammaherpesvirus 8; Betapolyomavirus hominis; Betapolyomavirus macacae |
| Sample organism |
Rattus norvegicus |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
Comparing the miRNA profile of exosomes from ASML vs ASML CD44v kd pancreatic adenocarcinoma line revealed that the expression level of 33 from the 40 most abundant miRNA differed significantly between ASMLwt and ASML-CD44vkd exosomes
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| Overall design |
In this study tumor cell exosomes, deemed important for intercellular communication were analysed for their miRNA content. Exosomes from a highly metastatic pancreatic adenocarcinoma cell line, ASML and from a CD44v kd of ASML were used for RNA preparation using Trizol reagent, and the total RNA was sent to Genomics core facility,EMBL, Heidelberg for miRCURY LNA microRNA Array, v.11.0 - hsa, mmu & rno
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| |
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| Contributor(s) |
Rana S, Zoeller M |
| Citation(s) |
23479506, 23190502 |
| Submission date |
Dec 27, 2011 |
| Last update date |
Sep 19, 2019 |
| Contact name |
Sanyukta Rana |
| E-mail(s) |
s.rana@uni-heidelberg.de
|
| Organization name |
University Hostipal Heidelberg
|
| Department |
Tumor Cell Biology
|
| Lab |
AG Zoller
|
| Street address |
Im Neuenheimerfeld 365
|
| City |
Heidelberg |
| ZIP/Postal code |
69115 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL7723 |
miRCURY LNA microRNA Array, v.11.0 - hsa, mmu & rno |
|
| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE34739 |
Exosomal tumor miRNA modulates premetastatic organ cells |
|
| Relations |
| BioProject |
PRJNA156217 |
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