|
| Status |
Public on Jun 03, 2013 |
| Title |
Role and function of Ptpn6 in BCR-ABL1 driven pre-B cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In order to investigate the function of Ptpn6 in ALL, we isolated bone marrow cells from Ptpn6 +/fl mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE-ERT2 or ERT2 (PMIP) and after 2 days of treatment with 4OH-Tamoxifen (0.5 micromolar) subjected to gene expression analysis.
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| Overall design |
Two days after treatment with 4OH-Tamoxifen (0.5 micromolar) total RNA of Puromycin resistant cells was extracted and subjected to gene expression analysis.
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| Contributor(s) |
shojaee s |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jan 03, 2012 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Markus Müschen |
| E-mail(s) |
mmuschen@chla.usc.edu
|
| Phone |
+ 1 323 361 5592
|
| Fax |
+1 323 361 1516
|
| URL |
http://www.lymphocytes.de/
|
| Organization name |
University of Southern California
|
| Department |
Childrens Hospital Los Angeles
|
| Lab |
Müschen Lab
|
| Street address |
4650 Sunset Blvd
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90027 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA150231 |
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